fat loss
Quality Rating
Buy AICAR 50mg
AMPK activator — mimics exercise metabolism, enhances endurance and fat oxidation
AMPK activation44% endurance increase in researchExercise mimetic
Who This Is For
Endurance athletes seeking metabolic optimization, or users wanting exercise-mimetic fat oxidation enhancement alongside their training.
Overview & Benefits
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMPK activator that triggers the same metabolic cascade as sustained aerobic exercise. By activating AMPK, AICAR upregulates fat oxidation, increases mitochondrial biogenesis, improves glucose uptake, and enhances endurance capacity at the cellular level.
The compound achieved notoriety from research showing it increased running endurance in sedentary mice by 44% and produced measurable fat loss without any exercise. It is not a stimulant and does not affect the CNS — the effect is purely metabolic. Used by athletes to boost endurance adaptation and metabolic efficiency alongside training, or by researchers studying exercise mimicry.
Key Benefits
- Activates AMPK — the master metabolic switch triggered by exercise
- Increases fat oxidation and mitochondrial biogenesis
- 44% endurance increase in sedentary animals without training
- Improves insulin sensitivity and glucose uptake
- Non-stimulant — purely metabolic mechanism with no CNS effects
Protocols & Dosing
Endurance Enhancement Protocol
Once daily500mg–1g subcutaneous or IV
Typically run for 4-week cycles. Inject before endurance training for synergistic metabolic effect. Do not use as a replacement for exercise — amplifies training adaptation.
Buy AICAR 50mg
$69.99
Buy Now — $69.99Buy at PhiogenResearch-grade · COA verified · Phiogen
Categoryfat loss
Typeinjectable
Quality Rating★★★★☆
VendorPhiogen
AICAR 50mg
$69.99